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Phagocytosis was observed at min after mixing macrophages wi
2022-10-04

Phagocytosis was observed at 60 min after mixing macrophages with microbes (A). The phagocytosis ability (PA) and phagocytosis index (PI) values of the macrophages engulfing the bacteria measured in flow cytometer were shown in histograms (B). Statistical analyses revealed that both the PA and PI va
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In conclusion we have identified ten novel GPCR
2022-10-04

In conclusion, we have identified ten novel GPCR genes and a pseudogene. Transcripts for GPR78, GPR81, GPR94, GPR95, GPR101, GPR103 and P2Y were detected in various CNS and peripheral tissues. Given the high levels of identity observed within paralogous oGPCR gene clusters, future efforts will likel
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The need for an inflammatory risk profile was recently
2022-10-04

The need for an ‘inflammatory risk profile’ was recently discussed by several investigators. The present study is all the more significant in that it shows that a phenomenon that is influenced by various atherosclerotic risk factors and acute phase proteins is, indeed, associated with a less favorab
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MK-3207 HCl Introduction Since the development of the first
2022-10-02

Introduction Since the development of the first radioimmunoassay (RIA) to measure hormone levels in the late 1950s, for which Rosalyn Sussman Yalow was awarded the Nobel Prize for Medicine in 1977 (the second woman ever receiving it), the use of MK-3207 HCl in molecular research has increased trem
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br Material and methods br
2022-10-02

Material and methods Results and discussion Discussion It is well established that the guanosine-rich DNA sequences within telomeric DNA repeats, and in the promoter regions of a number of oncogenes or proto-oncogenes such as c-myc [20,23], VEGF [28,48,49] and Bcl-2 [21,50], can readily ass
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EZH interaction with HADC and HDAC through the EED
2022-10-02

EZH2 interaction with HADC1 and HDAC2 through the EED subunit is known to recruit histone deacetylases [113,114]. Given that PRC2-mediated repression of transcription may be partly dependent on the function of HDACs in specific cell contexts [115], the leukemia cell treatment with hydroxamic NS 1738
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br Conflicts of interest br Acknowledgments This work was
2022-10-02

Conflicts of interest Acknowledgments This work was supported by the Project of Huzhou Municipal Science and Technology Bureau of Zhejiang Province (No. 2016GY45 to YGC) and he Project of Zhejiang Basic Public Benefit research of Zhejiang Province (No. LGF18H160005 to YGC) Introduction Wit
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Genome wide binding and transcriptome analyses demonstrate t
2022-10-02

Genome-wide binding and transcriptome analyses demonstrate that Fbxl10 directly binds the Areg, Mdk, Lmnb1, Thbs1, Mgp and Cxcl12 locus and thereby might influences the expression of these migration associated genes. The expression of epidermal growth factor (EGF)-like molecule Amphiregulin (Areg)
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br HO and cerebral malaria In a post mortem
2022-10-02

HO-1 and cerebral malaria In a post-mortem evaluation of human cerebral (falciparum) malaria, strong HO-1 immunostaining was consistently noted in microglia/macrophages within and surrounding the pathognomonic Durck’s granulomas (Schluesener et al., 2001). As witnessed in cerebral trauma specimen
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br Materials and methods br
2022-10-01

Materials and methods Results Discussion D. abbreviatus larvae are voracious feeders, and the nutrients consumed as part of their diet are broken by gut proteases and utilized for growth and development. Since proteases play an important role in larval and adult food digestion, it is import
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By combining the results of the
2022-10-01

By combining the results of the melting curve analysis of exon 5 and exon 6, the allelic setup of our 250 subjects was determined; the four allelic variants are shown in Table 1. However, GSTP1-1 *A/*C and GSTP1-1 *B/*D could not be distinguished from one another because both genotypes are character
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A major hurdle in purifying a membrane
2022-09-30

A major hurdle in purifying a membrane protein is finding a detergent that can preserve the protein, after releasing it from a given membrane, in a stable and non-aggregated state during purification steps [18,50]. The ability of various detergents used to solubilize and purify membrane proteins has
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br Results and discussion br Conclusion In conclusion we des
2022-09-30

Results and discussion Conclusion In conclusion, we designed and synthesized a novel series of thiosemicarbazide-1,2,3-triazole hybrids 10a-o. Further, α-glucosidase inhibitory activity of the synthesized compounds 10a-o was evaluated. The obtained results showed that all the synthesized thios
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Rifabutin sale br Acknowledgements This work was supported
2022-09-30

Acknowledgements This work was supported by the National Institutes of Health [grant number GM024417]. Introduction In mammals, glucose is the major energy substrate supporting conceptus development after Rifabutin sale formation [1,2]. While the equine morula uses similar amounts of pyruvat
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GCK MODY is the most common form of MODY
2022-09-30

GCK-MODY is the most common form of MODY diabetes in many populations (Chevre et al., 1998; Massa et al., 2001; Barrio et al., 2002; Estalella et al., 2007; Pruhova et al., 2010; Capuano et al., 2012; Giuffrida et al., 2017). However, data about GCK-MODY among North African populations are very rare
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